Molecular simulations of neuronal ion channel function

Type de poste
Niveau d'étude minimal
Durée du poste
Contrat renouvelable
Contrat non renouvelable
Date de prise de fonction
Date de fin de validité de l'annonce
Nom de la structure d'accueil

13 rue Pierre et Marie Curie
75005 Paris

Jérôme Hénin
Email du/des contacts

Ligand-gated ion channels such as nicotinic acetylcholine receptors are membrane proteins that perform a unique function: transducing chemical signals into electric impulses in neurons or muscular cells. In this project the candidate will use molecular simulations to understand in detail the complex landscape that these proteins navigate during their functional motions, as well as the modulation of these motions by natural and exogenous molecules. This completely interdisciplinary project will leverage state-of-the-art methods in molecular simulation, and potentially trigger new developments, driven by major biomedical questions.

The work is fully funded for three years. The lab offers an extremely rich and supportive scientific environment. Dr Hénin has expertise on the science of ligand-gated channels as well as state-of-the-art simulation methods. There are local computational resources (CPUs and GPUs), and an initial allocation of computer time is already secured at national supercomputer centers.

Equipe adhérente personne morale SFBI
Equipe Non adhérente