Single cell RNAseq analysis

Type de poste
Niveau d'étude minimal
Dates
Durée du poste
Contrat renouvelable
Contrat non renouvelable
Date de prise de fonction
Date de fin de validité de l'annonce
Localisation
Nom de la structure d'accueil
Adresse

1 impasse des ateliers
94400 Vitry Sur Seine
France

Contacts
Ana Maria Florescu
Email du/des contacts
ana-maria.florescu@sanofi.com
Description

The purpose of this project would to benchmark classification methods for single cell data. The recent droplet based techniques produce high throughput , but also noisier data than the first generation of methods. In this context it is important to understand how this impacts the power of cell type classification methods, and especially methods that are based on signatures. We will compare a series of publicly available methods ranging from MCP Counter, GSVA and going to more sophisticated classification methods like Garnett and ACTINN. The final objective is to produce a series of best practices that could be applied to analyzing internally generated data.

Desired competencies: programming (R prefereable), statistics, bioinformatics, machine learning, immunology

Equipe adhérente personne morale SFBI
Equipe Non adhérente