RNASeq

BiGR

Acronyme ou nom de la structure
Nom complet (en toutes lettres)
Bioinformatics platform, Gustave Roussy
Adresse

Plateforme de bioinformatique BiGR
UMS AMMICA
INSERM US23 / CNRS UMS3655
PF de l'Institut Français de Bioinformatique (IFB)
Bâtiment B2M - étage 1 - pièce 136
114, rue Édouard-Vaillant

94805 Villejuif Cedex - France
France

Téléphone
0142114112
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BF2I

Acronyme ou nom de la structure
Nom complet (en toutes lettres)
Atelier de Bioinformatique
Adresse

INSA Bâtiment Louis Pasteur
20 avenue Albert Einstein

69621 Villeurbanne cedex
France

Téléphone
+33 (0)4 72 43 83 56
Fax
+33 (0)4 72 43 85 34
Description (English)

Research at BF2I is focused on the comprehension of the functions managing the interaction of specific insect pests (aphids and weevils) with their direct biological partners (host plants and symbiotic microorganisms). Research approaches are multi-disciplinary thanks to the different expertise of the staff members.

The central theme of our research is to understand the relationships established between insects and their symbionts elucidating the molecular mechanisms that allow the establishment, maintenance and persistence of these complex interactions in multiple insect generations.

The final goal of research on these complex biological interactions, often involving multiple partners in interaction with the environment, is to identify tools and define new concepts for an integrated approach for plant protection against insect pests. Our research results are to be central for the development of agricultural practices that are sustainable, and respect both the environment and human health.

English keywords
symbiosis, insect pests, functional genomics, systems biology
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IBENS-GPC

Acronyme ou nom de la structure
Nom complet (en toutes lettres)
Plateforme génomique de l'IBENS
Adresse

75230 Paris Cedex 05, France
France

Description (English)

The genomic platform of the Institut de Biologie de l’École normale supérieure (IBENS) assists you in high throughput functional genomics projects. Our 15-year experience in transcriptomic analysis and an ISO-9001 quality approval guarantee us precision and traceability when treating your samples.

We are charter member of the network « Genomic Paris Centre », in partnership with Institut Curie and Université Pierre et Marie Curie (UPMC). We are approved by the Infrastructures en Biologie Santé et Agronomie (IBiSA) and are part of the France Génomique consortium.

We offer our help in every aspect of your genomic projects. Whether you have questions about funding request, experimental design, management of your samples, use of our equipment, data analysis or training, we are here to help. Do not hesitate in visiting the website to discover our activities. You can go to the contact page if you wish to know more about us.

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SBDM

Acronyme ou nom de la structure
Nom complet (en toutes lettres)
Systems Biology of Decision Making
Adresse

Laboratory of Biology and Modeling of the Cell
UMR5239
Ecole Normale Supérieure de LYON
Site Jacques Monod, Bâtiment LR3.
46 allée d’Italie -

69354 LYON cedex 07
France

Description (English)

The molecular mechanisms controlling decision making at the cellular level between self-renewal and differentiation are still poorly understood. The central question of our group consists in understanding the molecular mechanisms controlling self-renewal and the alteration of these mechanisms in relation to the onset of cancer.

For this we abide by the following view : "The stem-cell signature should therefore be determined by systems-biology tools that can identify patterns, rather than by the analysis of individual genes or even multiple gene-product behaviours." Zipori, D. (2004) The nature of stem cells : state rather than entity. Nat. Rev. Genet., 5, 873-878.

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