Post-doc / IR

Nucléosomes, expression génique, et cycle cellulaire

Le laboratoire s'intéresse à comment les cellules de mammifère en prolifération transmettent de l’information régulatrice aux cellules filles. Nos modèles principaux sont les cellules souches embryonnaires et les cellules cancéreuses. Les questions sont abordées par des techniques dites de OMICs (RNA-seq, ChIP-seq, ATAC-seq, MNase-seq) et visent à comprendre l’état de régulation génique pendant la division cellulaire et comment cela influence les prises de décisions cellulaires par les cellules filles.

Notation and ranking of subgraphs extracted from biological knowledge graphs

The post-doctoral project concerns the analysis of complex interaction networks. The main ressource at our disposal is a huge heterogeneous graph database (provided by EdgeLeap for the FIGHT-HF program) that represents various types of interactions between various groups of elements : proteins, diseases, drugs, etc. One objective of the FIGHT-HF project is to exploit this ressource to identify new biomarkers characteristics of certain heart-failure mechanisms.

Post-doctoral fellow in method development for Structural Variation detection

A 2-year post-doctoral fellowship is available at the Inria Genscale team in Rennes (France) to work on the development of novel computational methods for the detection and analysis of structural variations with linked-read sequencing data with Dr Claire Lemaitre and colleagues (http://people.rennes.inria.fr/Claire.Lemaitre/).