Analysis of Genomic Variants in Children and Young Adults with Acute Myeloid Leukemia

Type de poste: 
Durée du poste: 
24 mois
Date de début: 
Sa, 01/12/2018
Analyse Bioinformatique ARTbio

Plateforme de bioinformatique ARTbio
Institut de Biologie Paris Seine | Sorbonne-Université
Bâtiment B, 7e étage, porte 725
9, Quai St Bernard, - Case Courrier 25
75252 Paris Cedex 05

Nom et prénom du contact: 
Antoniewski Christophe
Email du contact: 
Christophe [dot] antoniewski [at] sorbonne [dot] universite [dot] fr
Date de validité: 
Description du poste: 
A 2-year IR/postdoc position of genomic data analyst is available to work at a  research project  "COllaborative NEtwork on research for Children and Teenagers with Acute Myeloblastic Leukemia" CONECT-AML. The project is funded by the INCA and involves 10 participant teams across France, with clinical or fundamental approaches.
The candidate will work in [ARTbio]( that is a participant team of CONECT-AML. ARTbio is the bioinformatic facility of the [Institut de Biology Paris Seine]( located on the campus Jussieu of the Sorbonne-Université.
The work package includes (i) better characterization of genetic abnormalities associated with AML in children and adolescents; (ii) Search for new predispositions; (iii) Study of myeloid leukemogenesis in three contexts of known predisposition -- congenital neutropenia, GATA2 mutation and Fanconi anemia.
Good knowledge and experience in NGS analysis (WES, WGS, RNAseq) are mandatory, as well as experience in analysis of rare genomic variants.
Excellent skills in Python and R are required, and solid expertise in the framework Galaxy as well as knowledge in Genetics of Human Diseases would be a plus.
Contact: Christophe [dot] antoniewski [at] sorbonne-universite [dot] fr for ARTbio, arnaud [dot] petit [at] aphp [dot] fr for CONECT-AML