Simulating the cortical activity evoked by artificial retinal implants

Type de poste
Niveau d'étude minimal
Durée du poste
Contrat renouvelable
Contrat non renouvelable
Date de prise de fonction
Date de fin de validité de l'annonce
Nom de la structure d'accueil

2004, route des Lucioles – BP 93
06902 Sophia Antipolis

Bruno Cessac,
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Recent advances in neuroscience and microelectronics opens up the possibility of partially restoring vision to blind patients using retinal prostheses. The group of F. Chavane (NeOpTo team at INT Marseille) has used mesoscopic recordings of cortical activity (optical imaging) to better understand the activity evoked by stimulation of the retina with implanted multi electrodes arrays (Roux et al 2016 eLife). Their results show that local stimulation of the retina evoked a cortical activity that is up to 10 times larger than what is expected based on the activity evoked by visual stimuli. This result is in line with known poor resolutions of percepts evoked by stimulation of artificial retinas implanted in blind patients.
This internship aims at predicting the dynamics of neuronal activity when the prosthesis emits a spatio-temporal stimulation pattern and compare with visual stimulation. The internship will be done in collaboration between Bruno Cessac (Biovision, INRIA, Sophia- Antipolis), F. Chavane and S. Roux (INT, CNRS, Marseille). The duration is 6 months. The internship will be done at INRIA with several visits to INT. The candidate is expected to have a strong background in programming (C++, git, cmake). He/she must also have a great interest in the field of visual neuroscience, both for fundamental aspects of visual processing and clinical research.

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