601 rue de la chimie
We offer a PhD position in co-tutelle between the University of Geneva and the University of Grenoble-Alpes. The topic is related to the study of carbohydrate-binding proteins (lectins) and involves the UniLectin portal (unilectin.eu), composed of UniLectin3D, a database with more than 2000 3D-structures of lectins and LectinPred, a prediction toolbox based on the lectin structure classification to screen available genomes.
The project includes extending the sequence coverage of lectins, modeling carbohydrate binding domains in the new lectins predicted in genomes, predicting specificity towards complex oligosaccharides, and improving lectin domain annotation.
The PhD is planned as follows:
First 18 months in CERMAV – Centre de Recherches sur les Macromolecules Végetales (cermav.cnrs.fr) affiliated to the University of Grenoble Alpes and next 18 months in the Proteome Informatics Group of SIB Swiss Institute of Bioinformatics (www.sib.swiss/frederique-lisacek-group) integrated in the University of Geneva (cui.unige.ch). The two teams collaborate on the development of bioinformatics tools for the study of glycosciences, with complementary expertise.
The candidate should be able to interact with two different teams, working in different domains. Adaptability, sociability and eagerness to learn will be key requirements, as well as being able to work independently.