Integrative molecular signatures of metastatic patients

Type de poste
Niveau d'étude minimal
Durée du poste
Contrat renouvelable
Contrat non renouvelable
Date de prise de fonction
Date de fin de validité de l'annonce
Nom de la structure d'accueil


Sergey Nikolaev
Daniel Gautheret
Email du/des contacts



Postdoctoral position in bioinformatics or computational biology.

Project title:

Integrative molecular signatures of metastatic patients

Research environment and project

Gustave Roussy, the premier European Cancer Centre, recruits a bioinformatics or computational biology postdoctoral fellow at Institut Hospitalo-Universitaire (IHU) PRISM led by Pr. Fabrice André. IHU PRISM is a joint project of Gustave Roussy, Université Paris-Saclay and other education/research institutions that aims at modeling cancer using integrative patient data for the development of novel precision medicine therapies.

The postdoctoral fellow will have access to a unique molecular sequence dataset (RNA and DNA) for hundreds of metastatic tumors. Her/his mission will be to identify heterogeneous molecular signatures associated to different clinical variables in order to improve understanding of the metastatic progression in a patient-specific context. Model building and validation will also exploit available public databases. 

The successful candidate will be supported on the longer term to apply for CNRS/INSERM starting grants and positions in order to establish his/her own research group at Gustave Roussy.


Applicants should have doctoral experience in human genome/transcriptome data analysis and/or machine learning, with a desire and capacity to acquire complementary expertise, including in oncology. Valued skills for this position include: transcriptomics, germline or somatic DNA variation analysis, multi-omics integrative models, statistical classification, gene network and gene module analysis.

In order to apply to CNRS or INSERM starting grants, a solid doctoral and postdoctoral publication track record is necessary.

The postdoctoral fellow will be self-motivated and able to work independently and get actively involved with colleagues of the PRISM institute.

Qualifications : 

Ph.D. in bioinformatics, computational biology, biostatistics or machine learning.   

Contract type:

Initial fixed-term 24-month contract, with possible extension. Salary dependents on experience.  

For queries about this position, please contact:


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