Acronyme ou nom de la structure
Nom complet (en toutes lettres)
Systems Biology of Decision Making

Laboratory of Biology and Modeling of the Cell
Ecole Normale Supérieure de LYON
Site Jacques Monod, Bâtiment LR3.
46 allée d’Italie -

69354 LYON cedex 07

Description (English)

The molecular mechanisms controlling decision making at the cellular level between self-renewal and differentiation are still poorly understood. The central question of our group consists in understanding the molecular mechanisms controlling self-renewal and the alteration of these mechanisms in relation to the onset of cancer.

For this we abide by the following view : "The stem-cell signature should therefore be determined by systems-biology tools that can identify patterns, rather than by the analysis of individual genes or even multiple gene-product behaviours." Zipori, D. (2004) The nature of stem cells : state rather than entity. Nat. Rev. Genet., 5, 873-878.

Membre de la SFBI