Bioinformatic engineer

 CDD · IE  · 12 mois (renouvelable)    Bac+5 / Master   Institute for Research on Cancer and Aging of Nice (IRCAN) · Nice Cedex 02 (France)  2096€ brut/month (~1600€ net)

 Date de prise de poste : 1 octobre 2021


database variants web development human genome personalized medicine


Position: Bioinformatic engineer

Location: Laboratory of Gael Cristofari, Institute for Research on Cancer and Aging of Nice (IRCAN) at the University Cote d’Azur (Nice, France)

Contract: 1-year contract with possibility of extension


The position is funded by Inserm (French National Institute of Health and Medical Research) in frame of its cross-cutting program on Genomic Variability. Our team studies mobile element insertions, also known as transposable elements, and their role in generating genetic variations among humans. We developed an integrated database that provides a curated catalogue of such genetic variants, named euL1db, and accessible through a web interface. It plays an essential role to interpret whole genome sequencing experiments in the context of research or personalized medicine. Since its original design, massive amounts of new data sets have been publicly released and need to be curated and incorporated into the database. To achieve this, the infrastructure needs to be redesigned and optimized on both the server- and client-sides.

Related publication

Mir AA, Philippe C & Cristofari G. euL1db: the European database of L1HS retrotransposon insertions in humans. Nucleic Acids Res. 2015 Jan;43:D43-D47.

Main missions

  • Optimization of database architecture
  • Development of web applications and APIs (back-end and front-end)
  • Evaluation of new data sources from published articles, data set collection and curation
  • Generation of new data sets using existing tools
  • Database update and maintenance

Skills & qualifications

  • Master’s degree (MSc) in bioinformatics and/or database management and web development
  • High proficiency in relational databases (MySQL) and Python development
  • Experience in web application programming
  • Experience in project management and documentation (versioning, bug tracking, Markdown, Jupyter Notebook, etc)
  • Strong interest in and understanding of genomics concepts
  • Ability to read and understand original scientific articles in English to identify useful data sets
  • Ability to keep a high level of accuracy, attention to details and rigor
  • English: Good


Procédure : We are reviewing applications as they arrive. Thus, candidates are encouraged to submit their application as soon as possible and applications will be considered until we find a suitable candidate. The pre-selected candidates will be interviewed by Zoom. The earliest possible starting date is October 1st, 2021. To apply, please send to a single PDF file named "IE2021_NAME.pdf" with the email object "IE2021". The pdf file should contain the following documents (in the same order): - A complete CV (2 pages max) - A letter of motivation, explaining why your skills and previous experience are matching the work and responsabilities described in the offer description (2 pages max) - The contact information of 2 to 3 referees (including name, position, affiliation, email addresses and their link with the applicant) - Your Master’s academic record (subjects, grades, ranking)

Date limite : 15 août 2021


Gael Cristofari

Offre publiée le 21 juillet 2021, affichage jusqu'au 31 août 2021