Mots-Clés

single cell RNA sequencing spatial transcriptome cancer immunology

Description

We are looking for a highly motivated engineer for the lab of Julie Helft (Institut Cochin, Paris) who was recently awarded an ERC grant funding for 5 years.

The project include the analysis of single cell RNA sequencing and of spatial transcriptomic data generated from human and mouse tumors. The datasets will be generated by the lab and will also include publicly available datasets

The bio-informatician will be an author on the publication steming from the wet-lab

For more information please consult this publication from the lab: 

Nalio Ramos R, Missolo-Koussou Y, Gerber-Ferder Y, Bromley CP, Bugatti M, Núñez NG, Tosello Boari J, Richer W, Menger L, Denizeau J, Sedlik C, Caudana P, Kotsias F, Niborski LL, Viel S, Bohec M, Lameiras S, Baulande S, Lesage L, Nicolas A, Meseure D, Vincent-Salomon A, Reyal F, Dutertre CA, Ginhoux F, Vimeux L, Donnadieu E, Buttard B, Galon J, Zelenay S, Vermi W, Guermonprez P, Piaggio E, Helft J. Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer. Cell. 2022 Mar 31;185(7):1189-1207.e25. doi: 10.1016/j.cell.2022.02.021. Epub 2022 Mar 23. PMID: 35325594.

Required skills: 

• Master in Data science, Computer Science, Computational Biology, or related fields.  
• Previous experience in single-cell data analysis and/or multi-omics integration tools.  
• Strong programming (R and Python) skills will be a plus. 
• Previous experience in collaborations with wet-lab biologists will be a plus.

How to apply:

Send a CV and letter to julie.helft@inserm.fr