Mots-Clés
R,
Python
bash
Git
scRNA-Seq
bulk RNA-Seq
Chip-Seq
Description
About the Institute
The Institut Necker Enfants Malades (INEM), supported by INSERM, CNRS, and Université Paris Cité, is a leading biomedical research center located on the Necker campus in Paris. It hosts over 300 researchers dedicated to understanding human diseases. With state-of-the-art core facilities and strong collaborations with clinical departments, INEM offers a dynamic environment for both basic and translational research. The campus is internationally recognized for its pioneering work in transplantation, gene therapy, and biotherapies.
The Host Laboratory
The “Mechanisms and Therapeutic Strategies of Chronic Kidney Disease” team, led by Fabiola Terzi, investigates the molecular mechanisms driving chronic kidney disease (CKD) progression. The team collaborates closely with Marco Pontoglio’s “Epigenetics and Development” group, a leader in transcription factor and genetic network studies in kidney disease. Together, they have contributed to key discoveries involving the EGFR, mTOR/AKT, Lcn2, and more recently the HIPPO signaling pathways (Nat Cell Biol 2020, Nat Commun 2023, Cell Reports 2024).
Project and Responsibilities
The INEM Bioinformatics Hub is a collaborative platform dedicated to omics data analysis and integration. Its mission is to provide centralized support for data analysis, tool development, and bioinformatics training, fostering active exchange between biologists and computational scientists.
The recruited bioinformatician will:
- Support users (researchers, engineers, students) in analyzing omics datasets;
- Develop reproducible and adaptable analysis workflows for diverse experimental contexts;
- Contribute to bioinformatics scientific activities within the institute.
The position will be based primarily within Fabiola Terzi’s team, with opportunities to collaborate on other projects led by the Bioinformatics Hub.
Profile :
- Degree in bioinformatics, data science, or computational biology (Master’s, PhD, or equivalent);
- Experience with scRNA-seq, bulk RNA-seq, and ChIP-seq analyses;
- Demonstrated ability to handle large-scale multi-omics datasets;
- Proficiency in R, Python, bash, Git, and HPC environments;
- Knowledge of biological databases and FAIR principles;
- Strong teamwork, autonomy, and service-oriented mindset;
- Excellent communication and writing skills in English.
Practical Information :
- Contract duration: 1 year, renewable
- Salary: according to experience and Inserm pay scale
- Remote work: 1 day per week
- Start date: December 2025 or January 2026
- Application deadline: November 15, 2025
- To apply: Please send a detailed CV and a short paragraph describing your background and skills to : lamine.toure@inserm.fr