Mots-Clés
symbiosis
interactions
RNAseq
gene regulation
NGS
Description
A two-year post-doctoral position is available in the MAP (UM5240/INSA Lyon) and BF2i laboratory
(INRAE/INSA Lyon) to work on the molecular dialogue between weevils and their intracellular bacteria
through data analyses.
Starting date: First trimester 2026
Duration: two years
Funding: ANR ESSENTIAL
Project: The main objective of the ANR ESSENTIAL is to investigate the diversification of host-endosymbiont
interactions in cereal weevils by unraveling their genomic signatures, their regulatory innovations, and their
functions in symbiosis. The post-doctoral fellow will be involved in the study of different gene regulatory networks
between weevils and their endosymbionts by analysing dual-RNAseq datasets of symbiotic and aposymbiotic
weevils.
Fellow: The post-doctoral fellow will have a solid expertise in NGS data mining, especially in transcriptomic datasets.
Given the symbiotic nature of the model, the candidate should be familiar with both eukaryotic and prokaryotic
regulatory mechanisms, and able to efficiently explore the scientific literature to derive biologically meaningful
interpretations. The available data corresponds to multiple timepoints, symbiotic states, and weevil-endosymbiont
couples, making the project complex and requiring excellent organizational and analytical skills. The ideal candidate
is highly motivated, independent and productive, with a strong capacity to synthesize and interpret large datasets.
We are seeking an open-minded researcher, who enjoys working in multi-team, collaborative and dynamic
environment. The postdoctoral fellow will work in close interaction with three PhD students involved in the ANR
ESSENTIAL project.
Lab: The MAP laboratory is a joint research unit associating the CNRS (UMR5240), Claude Bernard Lyon 1 University
and INSA of Lyon (University of Lyon). The research of the Crp Team focuses on the regulatory mechanism including
structure of the chromosome, transcriptional factors and non-coding RNA. The team aims to develop integrative
model of bacterial genetic regulation using a variety of approaches (e.g. genomics, transcriptomics, molecular
genetics and computational modeling). The BF2i laboratory is affiliated to both INRAE and INSA Lyon. The research
focuses on the biology of different types of interactions involving insects and symbiotic bacteria. It also aims at
investigating emerging technologies required for insect pest control.
Environment: Lyon is built around the Rhône and Saône rivers. It is the second economic French city and its rich
history and architecture made it part of the Unesco World Heritage. The city is also culturally very dynamic. Within
France, Lyon has a strategic geographical position, close to the Alps and the Mediterranean coast, Switzerland and
Italy. Paris is only two hours away by TGV. Last but not the least, Lyon is considered the French capital of gastronomy,
offering a wide variety of food and wine from the surrounding areas.
Contact:
Florence Hommais (Florence.hommais@univ-lyon1.fr)
Rita Rebollo (rita.rebollo@inrae.fr)
Nicolas Parisot (nicolas.parisot@insa-lyon.fr)