Mots-Clés
epigenetics
bioinformatics
biostatistics
genomics
Description
Location: Lille, France
Institution: EGID (European Genomic Institute for Diabetes), INSERM, University of Lille
Research unit: METAB-OMICS (UMR1283 / U8199)
Supervisor: Dr Amna Khamis
Funding: EFSD / Novo Nordisk Foundation
Start date: April 2026
We are seeking a highly motivated postdoctoral researcher to lead an exciting research project funded by the EFSD / Novo Nordisk Foundation. The successful candidate will have expertise in bioinformatics, biostatistics, multi-omics integration, and/or epigenomics.
The project investigates epigenetic regulation in human pancreatic islets and key metabolic tissues, leveraging state-of-the-art DNA methylation, transcriptomic, and genetic datasets. The postdoctoral researcher will play a central role in developing and applying integrative biostatistical pipelines to identify functional (epi)genetic regulators of type 2 diabetes risk and progression. This work is anchored in deeply phenotyped human cohorts and offers a unique opportunity to work with high-resolution, multi-omic data in a translational research environment.
Responsibilities
• To lead statistical analysis and plan development of large-scale methylation, RNA-seq, ATAC-seq and genotype datasets, and multi-tissue integration analyses
• Develop predictive methylation and polygenic risk scores
• Contribute to scientific publications and international collaborations
• Provide supervision to junior researchers working on related or adjacent projects
Profile
• PhD in bioinformatics, biostatistics, computational biology, or a related quantitative field
• Strong proficiency in R and experience with large-scale multi-omic data analysis pipelines
• Ability to work independently while contributing effectively within a multidisciplinary team
• Excellent communication skills
• Fluent in English (spoken and written)
About us
The postdoctoral researcher will join the epigenomics group led by Dr Amna Khamis, based at Inserm U1283 (METAB-OMICS) within the European Genomic Institute for Diabetes (EGID) in Lille. EGID is a centre of excellence recognised through the French Laboratory of Excellence (LabEx) initiative and is directed by Philippe Froguel.
The successful candidate will work in a highly interdisciplinary and international research environment, interacting closely with experts in bioinformatics, biostatistics, epigenetics, transcriptomics, and functional biology, including collaborations with teams led by Amélie Bonnefond (DR, Inserm).
To apply
Please send a CV to: amna.khamis@cnrs.fr