Société Française de Bioinformatique

Mots-Clés

RNA-seq RIP-seq lncRNA non-coding RNA plant biology

Description

Our bioinformatics group at I2BC Gif sur Yvette is recruiting a computational biology postdoc to study plant long noncoding RNAs. As part of an ANR-funded project with the Plant Sciences Institute Paris-Saclay (IPS2), we investigate plant lncRNA roles in RNA splicing and protein binding, as well as their biological roles in drought resistance. We will use conventional bioinformatics pipelines as well as reference-free methods to study inter-species conservation of RNA expression and RNA-protein binding events.

Specific analyzes will involve:
* Set up NGS data analysis pipelines (RNA-seq and RIP-seq)
* Compare transcriptome and RIP-seq data across species
* Analyze results in terms of evolutionarily conserved functions
* Ensure compliance with FAIR principles in computational procedures

I2BC is a large molecular and cellular biology institute located in a pleasant environment 25 km from Paris (Gif-sur-Yvette). Our team (Computational Genome Biology) is part of the Genome Biology Department. The local bioinformatics environment is very rich, with discussion forums, seminars and training courses in bioinformatics, a bioinformatics platform, and a high-performance computing center.

Expected Skills

• Doctoral-level expertise in RNA biology (essential)
• Bioinformatics tools and concepts for NGS data analysis (genome/transcriptome/interactome)
• Proficiency in Python and R
• Proficiency with at least one workflow management system
• Good bioinformatics practices
• English level B1
• Strong interpersonal and communication skills
• Curiosity and dynamism
• Ability to manage numerous interactions and work on diverse projects