Mots-Clés
statistical genetics
genetic epidemiology
Whole genome sequencing
association study
infectious diseases
Description
The Laboratory of Human Genetics of Infectious Diseases (HGID, Director: Pr Jean-Laurent Casanova) is looking for a motivated and qualified Post-Doctoral fellow in statistical genetics and/or genetic epidemiology for the computational and statistical genetics team of the lab, under the supervision of Dr Aurélie Cobat.
The HGID laboratory is an international INSERM unit structured across two sites: the Necker branch (INSERM U1163, Institut IMAGINE), located at Necker-Enfants Malades Hospital in Paris, and the Rockefeller branch (St. Giles Laboratory of Human Genetics of Infectious Diseases) at Rockefeller University in New York. Our research is organized into five complementary teams, including a statistical and computational genetics group led by Dr. Cobat in Paris and Dr. Zhang in New York, alongside four experimental genetics teams focusing on mycobacterial infections, cutaneous viral infections, viral infections of the lung and brain, and anti-cytokine autoantibodies.
The aim of the statistical and computational genetics team is to identify candidate variants underlying human infectious diseases. Our general approach relies on in-depth analyses of large-scale sequencing (whole exome and whole genome sequencing) of cohort of patients and controls.
The selected candidate will be involved in projects on the genetic background of human infectious diseases. He/she will utilize existing tools and software packages while also tailoring and developing them to meet the specific project goals. In addition, this person will interact with a team of statistical geneticists and wet-bench investigators. The position requires a highly dynamic, interactive and communicative attitude.
Qualifications:
Ph.D. in statistical genetics, genetic epidemiology, biostatistics, or related field with strong quantitative background.
Experience with the statistical analysis of next-generation sequencing human data.
Proficiency with at least one programming language (R, Python and/or Perl are preferred) and with bash/shell scripting.
Writing of scientific publications and reports
Presentation of study results at international conferences
High motivation with strong English communication skills.
Additional information about our laboratory is available at http://www.hgid.org/, and about our Institute is available at http://www.institutimagine.org/en/.
The position is available as soon as possible, and is offered for one year but may be extended in principle. Salary will depend on previous experience.
Interested candidates should submit their application (CV, cover letter and reference contacts) by email to Aurélie Cobat (aurelie.cobat@inserm.fr)
Human Genetics of Infectious Diseases
INSERM / Université Paris Descartes - Unité 1163
Institut Imagine
24 Bd du Montparnasse
75015 PARIS
France
Tel: (33) 1 42 75 43 17