Mots-Clés
RNA-seq
Python/R
Cancer Research
Multi-omics Data Analysis
High-dimensional Data Analysis
Description
Context
This position is associated with the ARTURO project, funded by the European Commission under the Horizon Europe programme (Cancer Mission 2023).
International collaboration between Institut Curie and Assistance Publique Hôpitaux de Paris - Bichat hospital (France), Universidade Catolica Portugueasa and Fundação Gaspar Frutuoso (Portugal), University of Rome TorVergata and Humanitas University in Milan (Italy).
Coordinated by Dr Maria Carla Parrini.
https://www.arturoproject.eu
Therapy resistance remains a major challenge in oncology. Recent studies suggest that the intratumoral microbiome influences responses to anticancer treatments, particularly immunotherapy. The ARTURO project aims to better understand the role of bacteria and their metabolites in the tumor microenvironment and in drug response through an innovative 3D tumor-on-chip model integrating clinical data, multi-omics analyses, and state-of-the-art technologies. The research focuses on non-small cell lung cancer and invasive lobular breast cancer.
Missions
- Perform bioinformatics analyses of transcriptomics data (bulk RNA-seq, deconvolution, scRNA-seq, and Visium HD spatial transcriptomics).
- Interact on a daily basis with experimental scientists generating the data.
- Conduct scientific and technological monitoring relevant to the project.
- Communicate analysis results through meetings, written reports, and scientific publications.
Candidate Profile
Training and experience required
- Master’s degree or PhD in a field related to bioinformatics (the development of a PhD project on the topic is an available opportunity).
- Previous experience in the analysis of sequencing data (bulk RNA-seq, single-cell RNA-seq, and/or spatial transcriptomics).
Skills required
- Fluent in English.
- Analysis of high-dimensional omics data.
- Proficiency in high-level programming languages such as Python and/or R, and familiarity with good coding practices.
- Strong interest in the analysis of complex and heterogeneous biological datasets.
- Desired personal qualities: autonomy, organizational skills, teamwork, and the ability to work effectively in a multidisciplinary environment.
Contract information
Type of contract: Fixed-term contract
Starting date: January 2026
Duration: 18 months
Working time: full time
Gross annual salary: 29240 € to 36219 € according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 75%, supplementary health insurance
Location of the position: Paris