Société Française de Bioinformatique

Mots-Clés

Protein structure amyloid fibrils co-aggregation of proteins algorithms programming

Description

The main objective of our project is to develop computational tools for prediction of exogenous microbial proteins that can trigger amyloidosis in humans. This will pave the way for subsequent experimental tests that can be performed by the collaborators. To achieve the project objectives, we aim to develop bioinformatics tools that predict protein co-aggregation which will leverage knowledge of amyloid structures and, in particular, incorporate AI approaches.

Our team uses bioinformatics and computational biology methods to understand the principles of protein structure and biomolecular interactions (https://www.crbm.cnrs.fr/andrey-kajava/?lang=en). We are developing computational tools that enable large-scale, high-quality structural annotation of proteomes. (see https://bioinfo.crbm.cnrs.fr/index.php?route=home).

Candidate Profile: We seek a highly motivated student with a background in IT, strong programming skills (including Python), and a basic understanding of biology. The ideal candidate should have a good command of English, strong communication skills, and a keen interest in multidisciplinary research.

The scientific environment of the CRBM is international, multidisciplinary and very dynamic, in particular thanks to interactions with neighbouring institutes, and its resolutely collaborative and convivial spirit. Montpellier is a dynamic Mediterranean city with an exceptional environment, culture and quality of life.